Acute volume loading and exercise capacity in postural tachycardia syndrome

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Acute volume loading and exercise capacity in postural tachycardia syndrome.

Postural tachycardia syndrome (POTS) is associated with exercise intolerance, hypovolemia, and cardiac atrophy, which may contribute to reduced stroke volume and compensatory exaggerated heart rate (HR) increases. Acute volume loading with intravenous (iv) saline reduces HR and improves orthostatic tolerance and symptoms in POTS, but its effect on exercise capacity is unknown. In this study, we...

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Reduced stroke volume during exercise in postural tachycardia syndrome.

Postural tachycardia syndrome (POTS) is characterized by excessive tachycardia without hypotension during orthostasis. Most POTS patients also report exercise intolerance. To assess cardiovascular regulation during exercise in POTS, patients (n = 13) and healthy controls (n = 10) performed graded cycle exercise at 25, 50, and 75 W in both supine and upright positions while arterial pressure (ar...

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Postural Orthostatic Tachycardia Syndrome Exercise Training Versus Propranolol in the Treatment of the Postural Orthostatic Tachycardia Syndrome

We have found recently that exercise training is effective in the treatment of the postural orthostatic tachycardia syndrome (POTS). Whether this nondrug treatment is superior to “standard” drug therapies, such as -blockade, is unknown. We tested the hypothesis that exercise training but not -blockade treatment improves symptoms, hemodynamics, and renal-adrenal responses in POTS patients. Ninet...

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Postural tachycardia syndrome (POTS).

INTRODUCTION POTS is defined as the development of orthostatic symptoms associated with a heart rate (HR) increment >or=30, usually to >or=120 bpm without orthostatic hypotension. Symptoms of orthostatic intolerance are those due to brain hypoperfusion and those due to sympathetic overaction. METHODS We provide a review of POTS based primarily on work from the Mayo Clinic. RESULTS Females p...

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Postural tachycardia syndrome (POTS).

Postural Tachycardia Syndrome (POTS) Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2013 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/CIRCULATIONAHA.112.144501 2013;127:2336-2342 Circulation. http://circ.ahajournals.org/content/127/23/2336 World Wide Web at: The ...

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ژورنال

عنوان ژورنال: Journal of Applied Physiology

سال: 2014

ISSN: 8750-7587,1522-1601

DOI: 10.1152/japplphysiol.00367.2014